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1

The development and hepatotoxicity of acetaminophen: reviewing over a century of progress

McGill, Mitchell R., Hinson, Jack A.

Journal:

Drug Metabolism Reviews

Year:

2020

File:

PDF, 3.14 MB

2020

2

Cytokines and Toxicity in Acetaminophen Overdose

James, Laura P., Simpson, Pippa M., Farrar, Henry C., Kearns, Gregory L., Wasserman, Gary S., Blumer, Jeffrey L., Reed, Michael D., Sullivan, Janice E., Hinson, Jack A.

Journal:

Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 124 KB

english, 2005

3

Acetaminophen‐Induced Hepatotoxicity: Role of Metabolic Activation, Reactive Oxygen/Nitrogen Species, and Mitochondrial Permeability Transition

Hinson, Jack A., Reid, Angela B., McCullough, Sandra S., James, Laura P.

Journal:

Drug Metabolism Reviews

Year:

2004

Language:

english

File:

PDF, 225 KB

english, 2004

4

Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species

Sherryll L. Michael, Neil R. Pumford, Philip R. Mayeux, Michael R. Niesman, Jack A. Hinson

Journal:

Year:

1999

Language:

english

File:

PDF, 1.02 MB

english, 1999

5

A simple high-pressure liquid chromatographic assay for the N-hydroxy derivatives of phenacetin, acetaminophen, 2-acetylaminofluorene, and other hydroxamic acids

Jack A. Hinson, Lance R. Pohl, James R. Gillette

Journal:

Analytical Biochemistry

Year:

1980

Language:

english

File:

PDF, 482 KB

english, 1980

6

Chlorotyrosine protein adducts are reliable biomarkers of neutrophil-induced cytotoxicityin vivo

Jaspreet S Gujral, Jack A Hinson, Hartmut Jaeschke

Journal:

Comparative Hepatology

Year:

2004

Language:

english

File:

PDF, 1.02 MB

english, 2004

7

High-performance liquid chromatographic assay for acetaminophen and phenacetin in the presence of their metabolites in biological fluids

K. Sandy Pang, Ann Marie Taburet, Jack A. Hinson, James R. Gillette

Journal:

Journal of Chromatography A

Year:

1979

Language:

english

File:

PDF, 827 KB

english, 1979

8

Tumour Necrosis Factor Receptor 1 and Hepatocyte Regeneration in Acetaminophen Toxicity: A Kinetic Study of Proliferating Cell Nuclear Antigen and Cytokine Expression

Laura P. James, Richard C. Kurten, Laura W. Lamps, Sandra McCullough, Jack A. Hinson

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2005

Language:

english

File:

PDF, 292 KB

english, 2005

9

Hepatic necrosis caused by furosemide

MITCHELL, JERRY R., POTTER, WILLIAM Z., HINSON, JACK A., JOLLOW, DAVID J.

Journal:

Year:

1974

File:

PDF, 512 KB

1974

10

Acetaminophen toxicity to cultured rat embryos

Benjamin S. Weeks, Paul Gamache, Norman W. Klein, Jack A. Hinson, Mary Bruno, Edward Khairallah

Journal:

Teratogenesis, Carcinogenesis, and Mutagenesis

Year:

1990

Language:

english

File:

PDF, 688 KB

english, 1990

11

Selective Protein Covalent Binding and Target Organ Toxicity

Steven D. Cohen, Neil R. Pumford, Edward A. Khairallah, Kim Boekelheide, Lance R. Pohl, H.R. Amouzadeh, Jack A. Hinson

Journal:

Toxicology and Applied Pharmacology

Year:

1997

Language:

english

File:

PDF, 153 KB

english, 1997

12

Comments on “Blank reactor corrections in studies of the oxidative dehydrogenation of methane” by D. J. C. Yates and N. E. Zlotin

Masaharu Hatano, Paul G. Hinson, K. Shay Vines, Jack H. Lunsford

Journal:

Journal of Catalysis

Year:

1990

Language:

english

File:

PDF, 368 KB

english, 1990

13

Propanil-induced methemoglobinemia and hemoglobin binding in the rat

David C. McMillan, Tammie A. McRae, Jack A. Hinson

Journal:

Toxicology and Applied Pharmacology

Year:

1990

Language:

english

File:

PDF, 401 KB

english, 1990

14

Immunoblot analysis of protein containing 3-(cystein-S-yl)acetaminophen adducts in serum and subcellular liver fractions from acetaminophen-treated mice

Neil R. Pumford, Jack A. Hinson, R. Wayne Benson, Dean W. Roberts

Journal:

Toxicology and Applied Pharmacology

Year:

1990

Language:

english

File:

PDF, 1.79 MB

english, 1990

15

Metabolism of the arylamide herbicide propanil: I. Microsomal metabolism and in vitro methemoglobinemia

David C. McMillan, James P. Freeman, Jack A. Hinson

Journal:

Toxicology and Applied Pharmacology

Year:

1990

Language:

english

File:

PDF, 1.00 MB

english, 1990

16

Metabolism of the arylamide herbicide propanil: II. Effects of propanil and its derivatives on hepatic microsomal drug-metabolizing enzymes in the rat

David C. McMillan, Julian E.A. Leakey, Michael P. Arlotto, JoEllyn M. McMillan, Jack A. Hinson

Journal:

Toxicology and Applied Pharmacology

Year:

1990

Language:

english

File:

PDF, 1.86 MB

english, 1990

17

Role of metabolites in propanil-induced hemolytic anemia

David C. McMillan, Timothy P. Bradshaw, Jack A. Hinson, David J. Jollow

Journal:

Toxicology and Applied Pharmacology

Year:

1991

Language:

english

File:

PDF, 730 KB

english, 1991

18

Resveratrol, a dietary polyphenolic phytoalexin, is a functional scavenger of peroxynitrite

Joseph H. Holthoff, Kellie A. Woodling, Daniel R. Doerge, Samuel T. Burns, Jack A. Hinson, Philip R. Mayeux

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 265 KB

english, 2010

19

Indocyanine green clearance varies as a function of N-acetylcysteine treatment in a murine model of acetaminophen toxicity

Alessandra Milesi-Hallé, Susan M. Abdel-Rahman, Aliza Brown, Sandra S. McCullough, Lynda Letzig, Jack A. Hinson, Laura P. James

Journal:

Chemico-Biological Interactions

Year:

2011

Language:

english

File:

PDF, 989 KB

english, 2011

20

Acetaminophen hepatotoxicity and HIF-1α induction in acetaminophen toxicity in mice occurs without hypoxia

Shubhra Chaudhuri, Sandra S. McCullough, Leah Hennings, Lynda Letzig, Pippa M. Simpson, Jack A. Hinson, Laura P. James

Journal:

Toxicology and Applied Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.49 MB

english, 2011

21

Antagonism of bromobenzene-induced hepatotoxicity by phentolamine: Evidence for a metabolism-independent intervention

Brent D. Kerger, Stephen M. Roberts, Jack A. Hinson, Jay Gandy, Raymond D. Harbison, Robert C. James

Journal:

Toxicology and Applied Pharmacology

Year:

1988

Language:

english

File:

PDF, 637 KB

english, 1988

22

Echinomycin Decreases Induction of Vascular Endothelial Growth Factor and Hepatocyte Regeneration in Acetaminophen Toxicity in Mice

Alessandra Milesi-Hallé, Sandra McCullough, Jack A. Hinson, Richard C. Kurten, Laura W. Lamps, Aliza Brown, Laura P. James

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2012

Language:

english

File:

PDF, 641 KB

english, 2012

23

Acetaminophen-Induced Hepatotoxicity in Mice Lacking Inducible Nitric Oxide Synthase Activity

Sherryll L. Michael, Philip R. Mayeux, Thomas J. Bucci, Alan R. Warbritton, Lisa K. Irwin, Neil R. Pumford, Jack A. Hinson

Journal:

Year:

2001

Language:

english

File:

PDF, 245 KB

english, 2001

24

Effect of Inhibitors of Nitric Oxide Synthase on Acetaminophen-Induced Hepatotoxicity in Mice

Jack A. Hinson, Thomas J. Bucci, Lisa K. Irwin, Sherryll L. Michael, Philip R. Mayeux

Journal:

Year:

2002

Language:

english

File:

PDF, 331 KB

english, 2002

25

An examination of octanol and octanal metabolism to octanoic acid by horse liver alcohol dehydrogenase

Jack A. Hinson, Robert A. Neal

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1975

Language:

english

File:

PDF, 671 KB

english, 1975

26

A metabolite of acetaminophen covalently binds to the 56 kDa selenium binding protein

Neil R. Pumford, Brian M. Martin, Jack A. Hinson

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 694 KB

english, 1992

27

N-hydroxylation of p-chloroacetanilide in hamsters

Jack A. Hinson, Jerry R. Mitchell, David J. Jollow

Journal:

Biochemical Pharmacology

Year:

1976

Language:

english

File:

PDF, 289 KB

english, 1976

28

Role of sulfotransferase from rat liver in the mutagenicity of N-hydroxy-2-acetylaminofluorene in Salmonella typhimurium

Gerard J. Mulder, Jack A. Hinson, Wendel L. Nelson, Snorri S. Thorgeirsson

Journal:

Biochemical Pharmacology

Year:

1977

Language:

english

File:

PDF, 410 KB

english, 1977

29

Generation of reactive metabolites of N-hydroxy-phenacetin by glucuronidation and sulfation

Gerard J. Mulder, Jack A. Hinson, James R. Gillette

Journal:

Biochemical Pharmacology

Year:

1977

Language:

english

File:

PDF, 927 KB

english, 1977

30

Conversion of the N-O-glucuronide and N-O-sulfate conjugates of N-hydroxyphenacetin to reactive intermediates

Gerard J. Mulder, Jack A. Hinson, James R. Gillette

Journal:

Biochemical Pharmacology

Year:

1978

Language:

english

File:

PDF, 1.09 MB

english, 1978

31

Studies on the mutagenicity of N-hydroxy-2-acetylaminofluorene in the ames-salmonella mutagenesis test system

Larry S. Andrews, Jack A. Hinson, James R. Gillette

Journal:

Biochemical Pharmacology

Year:

1978

Language:

english

File:

PDF, 1.13 MB

english, 1978

32

Acetaminophen-induced hepatic glycogen depletion and hyperglycemia in mice

Jack A. Hinson, Joann B. Mays, Alex M. Cameron

Journal:

Biochemical Pharmacology

Year:

1983

Language:

english

File:

PDF, 1.41 MB

english, 1983

33

Immunochemical quantitation of 3-(cystein-S-yl)acetaminophen protein adducts in subcellular liver fractions following a hepatotoxic dose of acetaminophen

Neil R. Pumford, Dean W. Roberts, R.Wayne Benson, Jack A. Hinson

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 1019 KB

english, 1990

34

Interleukin 6 and hepatocyte regeneration in acetaminophen toxicity in the mouse

Laura P James, Laura W Lamps, Sandra McCullough, Jack A Hinson

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 740 KB

english, 2003

35

Induction of the nuclear factor HIF-1α in acetaminophen toxicity: Evidence for oxidative stress

Laura P. James, Brian Donahower, Angela S. Burke, Sandra McCullough, Jack A. Hinson

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 235 KB

english, 2006

36

Are oxidative mechanisms primary in ethanol induced Purkinje neuron death of the neonatal rat?

Dwight R. Pierce, Cody C. Cook, Jack A. Hinson, Kim E. Light

Journal:

Neuroscience Letters

Year:

2006

Language:

english

File:

PDF, 138 KB

english, 2006

37

Immunochemical detection of oxidized proteins

Keller, Randal J., Halmes, N. Christine, Hinson, Jack A., Pumford, Neil R.

Journal:

Chemical Research in Toxicology

Year:

1993

Language:

english

File:

PDF, 1.56 MB

english, 1993

38

A rapid method for preparing crystalline human hemoglobin and the separation of crystalline hemoglobin A in quantity

Jack A. Hinson, Thomas L. McMeekin

Journal:

Biochemical and Biophysical Research Communications

Year:

1969

Language:

english

File:

PDF, 1.11 MB

english, 1969

39

N-hydroxyacetaminophen: A microsomal metabolite of N-hydroxyphenacetin but apparently not of acetaminophen

Jack A. Hinson, Lance R. Pohl, James R. Gillette

Journal:

Year:

1979

Language:

english

File:

PDF, 283 KB

english, 1979

40

Ascorbic acid inhibits covalent binding of enzymatically generated 2-acetyl-aminofluorene-N-sulfate to DNA under conditions in which it increases mutagenesis in salmonella TA-1538

Larry S. Andrews, Jacquelene M. Fysh, Jack A. Hinson, James R. Gillette

Journal:

Year:

1979

Language:

english

File:

PDF, 309 KB

english, 1979

41

Acetaminophen-induced hepatotoxicity

Jack A. Hinson, Lance R. Pohl, Terrence J. Monks, James R. Gillette

Journal:

Year:

1981

Language:

english

File:

PDF, 493 KB

english, 1981

42

Bromobenzene and p-bromophenol toxicity and covalent binding invivo

Terrence J. Monks, Jack A. Hinson, James R. Gillette

Journal:

Year:

1982

Language:

english

File:

PDF, 374 KB

english, 1982

43

Effect of trifluoperazine on toxicity, HIF-1α induction and hepatocyte regeneration in acetaminophen toxicity in mice

Shubhra Chaudhuri, Sandra S. McCullough, Leah Hennings, Aliza T. Brown, Shun-Hwa Li, Pippa M. Simpson, Jack A. Hinson, Laura P. James

Journal:

Toxicology and Applied Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.63 MB

english, 2012

44

784 Serum acetaminophen adducts reliably distinguish acetaminophen toxicity from other causes of acute liver failure

Timothy J. Davern II, Laura P. James, Robert J. Fontana, Anne M. Larson, Julie Polson, Ezmina Lalani, Jack A. Hinson, William M. Lee

Journal:

Year:

2003

Language:

english

File:

PDF, 240 KB

english, 2003

45

Comparison of covalent binding of acetaminophen and the regioisomer 3′-hydroxyacetanilide to mouse liver protein

Anthony M. Matthews, Jack A. Hinson, Dean W. Roberts, Neil R. Pumford

Journal:

Toxicology Letters

Year:

1997

Language:

english

File:

PDF, 673 KB

english, 1997

46

The acetaminophen regioisomer 3′-hydroxyacetanilide inhibits and covalently binds to cytochrome P450 2E1

N.Christine Halmes, Victor M Samokyszyn, Thomas W Hinton, Jack A Hinson, Neil R Pumford

Journal:

Toxicology Letters

Year:

1998

Language:

english

File:

PDF, 154 KB

english, 1998

47

Deferoxamine delays the development of the hepatotoxicity of acetaminophen in mice

Jennifer G. Schnellmann, Neil R. Pumford, Donna F. Kusewitt, Thomas J. Bucci, Jack A. Hinson

Journal:

Toxicology Letters

Year:

1999

Language:

english

File:

PDF, 159 KB

english, 1999

48

Measurement of Serum Acetaminophen–Protein Adducts in Patients With Acute Liver Failure

Timothy J. Davern II, Laura P. James, Jack A. Hinson, Julie Polson, Anne M. Larson, Robert J. Fontana, Ezmina Lalani, Santiago Munoz, A. Obaid Shakil, William M. Lee

Journal:

Gastroenterology

Year:

2006

Language:

english

File:

PDF, 253 KB

english, 2006

49

Drug-induced Liver Disease || Mechanisms of Acetaminophen-Induced Liver Disease

Hinson, Jack A.

Year:

2013

Language:

english

File:

PDF, 1.09 MB

english, 2013

50

Covalent Binding of Xenobiotics to Specific Proteins in the Liver

Pumford, Neil R., Halmes, N. Christine, Hinson, Jack A.

Journal:

Drug Metabolism Reviews

Year:

1997

Language:

english

File:

PDF, 923 KB

english, 1997

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